Cortisol, Free 24-hour Urine

Overview

  • EPIC Code:
  • LAB382
  • Soft Test Code:
  • UCOR1
  • Send Out Test Code:
  • 11280X
Alternate Names
  • Cortisol Free, Urine
  • Free Cortisol, Urine
Clinical Significance

Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.


Specimen Collection & Preparation

Specimen Requirements

10.0 mL aliquot from a well mixed 24 hour Urine Collection in a Plastic Container


Alternate Specimen


TransportAndStorage

48 hours Ambient
7 days Refrigerated (Preferred)
2 Months Frozen


Collection Instructions

1. When starting the 24-hour period, urinate and discard (throw-away) this specimen. NOTE THE TIME
2. From that time on, collect all urine by urinating into a clean container and transfer into the provided container. 
DO NOT URINATE DIRECTLY INTO CONTAINER.
3. Try to pass the last urine just prior to the end of the 24 hour period. Add this urine into the container. 
4. Urine Specimen should be kept refrigerated during and after collection. 

Printable Patient Collection Instructions

English 24 Hour Urine Collection

Spanish 24 Hour Urine Collection 

Burmese 24 Hour Urine Collection

Arabic 24 Hour Urine Collection 


Minimum Volume

5.0 mL


Neonatal Volumne

Clinical Interpretation

Reference Range:

Cortisol, Free, Urine (mcg/24 hrs)
  Adult 4.0-50.0
  Pediatric  
  1-4 Years 0.9-8.2
  5-9 Years 1.0-30.0
  10-13 Years 1.0-45.0
  14-17 Years 3.0-55.0
Cortisol, Free, Urine (mcg/g creat)
  Adult 3.1-42.3
Creatinine, 24-Hour Urine (g/24 hours)
  3-8 Years 0.11-0.68
  9-12 Years 0.17-1.41
  13-17 Years 0.29-1.87
  Adult 0.63-2.50


Methodology:
  • Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)

Clinical Significance

Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

8 to 12 days


Coding & Compliance

CDM

01426901


CPT Coding

82530, 82570