SureSwab®, Ureaplasma species

Included Tests

U. parvum DNA, U. urealyticum DNA

Clinical Significance

Ureaplasma spp. have been linked to upper genitourinary tract infection and to premature labor and abortion. Recently, by molecular means two groups have been distinguished, U.parvum and U. urealyticum, with the former being more prevalent in the lower genital tract of healthy women. It is not clear which species more predominantly causes infection. Ureaplasma spp. appear to be opportunists when they infect the upper genitourinary tract. These organisms have also been targeted as having a possible role in infertility, although this remains a gray area

Patient Preparation

Male: Patient should not have urinated within one hour prior to collection

Specimen Requirements

MALE: 
    Urethral Swab collected in a APTIMA® Unisex Swab Kit (white label)

FEMALE: 
   Vaginal swab in 0.7 mL APTIMA® Vaginal Swab Collection Kit (orange label)

Alternate Specimen

Male: Minimum: 2 mL male urine collected in a APTIMA® urine transport tube
Male Urine: Direct patient to provide a first-catch urine (a maximum of 20-30 mL of the initial urine stream) into a urine collection cup free of any preservatives. 2 mL of urine specimen must be transferred into the APTIMA® urine specimen transport within 24 hours of collection and before being assayed. Use the tube provided in the urine specimen collection kit. The fluid (urine plus transport media) level in the urine transport tube must fall within the clear pane on the tube label

Rejection: Urine submitted in Non-Aptiva transport container or Female Urine

Female:
Vaginal swab in 0.7 mL APTIMA® Vaginal Swab in APTIMA® Unisex Swab Specimen Collection Kit

TransportAndStorage

14 days Ambient (transport)
14 days Refrigerated
30 days Frozen

Collection Instructions

MALE:
Male Urethral Swabs: Follow instructions in the APTIMA® Unisex Swab Specimen Collection Kit (white label).
Excess mucus should be removed prior to sampling.


FEMALE:
Vaginal Swabs: Follow instructions in the APTIMA® Vaginal Swab Collection Kit or Multitest Collection Kit (orange label).

Minimum Volume

0.3 mL

Neonatal Volumne

Reference Range:

U. parvum DNA	Not detected
U. urealyticum DNA	Not detected

Methodology:

• Real-Time Polymerase Chain Reaction

Clinical Significance

Ureaplasma spp. have been linked to upper genitourinary tract infection and to premature labor and abortion. Recently, by molecular means two groups have been distinguished, U.parvum and U. urealyticum, with the former being more prevalent in the lower genital tract of healthy women. It is not clear which species more predominantly causes infection. Ureaplasma spp. appear to be opportunists when they infect the upper genitourinary tract. These organisms have also been targeted as having a possible role in infertility, although this remains a gray area

CPT Coding

87798 x 2