Scleroderma Antibody

Overview

  • EPIC Code:
  • IMO87
  • Soft Test Code:
  • SCL70
Alternate Names
  • Anti DNA Topoisomerase I
  • Anti-SCL-70
  • Anti-Topoisomerase I Antibody
  • SCL-70
  • Scl-70 Antibody
Clinical Significance

A positive result indicates the presence of Scl-70 antibodies and suggests the possibility of scleroderma


Specimen Collection & Preparation

Specimen Requirements:

-OR-

1.0 mL Serum in a SST Gold Top Tube
Minimum Volume:
0.5 mL Serum*

* This volume does not allow for repeat testing

Transport and Storage:
  • Refrigerated (2-8°C): 48 Hours

    Transport refrigerated to Parkview Regional Medical Center within 48 hours of collection

Clinical Interpretation

Reference Range:

< 20 Units


Test Comments:

  < 20 Units: Negative
20-39 Units: Week Positive
40-80 Units: Moderate Positive
   >80 Units: Strong Positive


Methodology:
  • Enzyme Immunoassay (EIA)
Clinical Significance

A positive result indicates the presence of Scl-70 antibodies and suggests the possibility of scleroderma


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Friday
Departments
  • Immunology

Coding & Compliance

CDM

01426240


CPT Coding

86235