RBC Folate

Overview

  • EPIC Code:
  • LAB2938
  • Soft Test Code:
  • RBCF
  • Send Out Test Code:
  • 467 / 14178
Alternate Names
  • Folate Red Blood Cell
  • Folate, RBC
  • Folic Acid
  • Folic Acid, RBC
  • RBC
  • RBC Folic Acid
  • Red Blood Cell Folate
Clinical Significance

Folate levels have diagnostic significance in nutritional deficiencies, especially in cases of severe alcoholism, function damage to the upper third of small bowel, pregnancy and various forms of megoblastic anemia. Since serum folate levels are subject to rapid change reflecting diet and absorption, RBC folate may be a better diagnostic tool since the levels remain fairly constant.


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Whole Blood from a Lavender Top Tube - EDTA into an Amber Vial


Transport And Storage

Folate protected from light
5 days Ambient
5 days Refrigerated (preferred)

Hematocrit
48 hours Ambient
48 hours Refrigerated  (preferred)
Unacceptable Frozen
 


Collection Instructions

Protect from Light  whole blood to be poured into Amber Vial.

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.


Minimum Volume

0.2 mL Whole Blood


Neonatal Volume

Clinical Interpretation

Reference Range:

>280 ng/mL RBC


Methodology:
  • Immunoassay (IA)
Clinical Significance

Folate levels have diagnostic significance in nutritional deficiencies, especially in cases of severe alcoholism, function damage to the upper third of small bowel, pregnancy and various forms of megoblastic anemia. Since serum folate levels are subject to rapid change reflecting diet and absorption, RBC folate may be a better diagnostic tool since the levels remain fairly constant.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00912747


CPT Coding

82747


Medical Necessity Documentation

Recommended as outpatient testing only