Prolactin Dilutions for High-Dose Hook Effect

Patient Preparation

Patient should discontinue taking Biotin, Vitamin B7, or Vitamin H 48 hours before getting blood drawn

Reference Range:

Male: 2 - 18 ng/mL

Female 
Non-Pregnant: 3 - 30 ng/mL
Pregnant: 10 - 209 ng/mL
Post Menopausal: 2 - 20 ng/mL

10-fold and 100-fold dilution produced results consistent with the absence of high-dose hook effect.

Test Comments:

Patients taking vitamin supplements containing doses of > 5mg/day may have falsely decreased test results generated. Total prolactin measured using the Roche Cobas e immunoassay analyzer.

Methodology:

• Electrochemiluminescence (ECLIA)

CDM

01425182

CPT Coding

84146