Lupus Panel 4

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 36378
Alternate Names
  • ANAlyzer®
  • ANAlyzeR™ ANA, IFA with Reflex Titer/Pattern, Syst
  • ANAlyzeR™ ANA, IFA with Reflex Titer/Pattern, Systemic Autoimmune Panel 1
  • Antinuclear Antibody Screen,Systemic Lupus Erythematosus (SLE)
  • FANA
  • Fluorescent ANA
  • Lupus (12) Panel
  • Lupus Analyzer
  • Lupus Analyzer; Lupus Panel 4 with ANA, IFA with Reflex to Titer and Pattern
  • Lupus Panel 4 with ANA, IFA with Reflex to Titer and Pattern
  • Progressive ANA, Hep-2
  • Thyroiditis
Included Tests

ANA Screen,IFA, with Reflex to Titer and Pattern; DNA (ds) Antibody, Crithidia IFA with Reflex to Titer; Chromatin (Nucleosomal) Antibody; Sm Antibody; Sm/RNP Antibody; RNP Antibody; Sjogren's Antibodies (SS-A, SS-B); Scleroderma Antibody (Scl-70); Jo-1 Antibody; Centromere B Antibody; Complement Component C3c and C4c; Cardiolipin Antibodies (IgA, IgG, IgM); Beta-2-Glycoprotein I Antibodies (IgG, IgA, IgM); Rheumatoid Factor (IgA, IgG, IgM); Cyclic Citrullinated Peptide (CCP) Antibody (IgG); Mutated Citrullinated Vimentin (MCV) Antibody; Thyroid Peroxidase Antibodies (TPO)


Clinical Significance

This panel can be helpful in the diagnosis of systemic rheumatic disorders and other autoimmune diseases. Although the test for antinuclear antibodies (ANA) is strongly associated with systemic lupus erythematosus (SLE), the laboratory evaluation for individuals with clinical suspicion of a variety of autoimmune diseases often begins with an ANA screen. This panel simultaneously tests for ANA (using immunofluorescence) as well as the important specific autoantibodies associated with a positive ANA. It also includes testing for complement proteins, rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, polymyositis, anti-phospholipid antibody syndrome, and autoimmune thyroid disease.


Specimen Collection & Preparation

Patient Preparation

Overnight fasting is preferred


Specimen Requirements
Transport And Storage


Collection Instructions


Minimum Volume

6.0 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

See Laboratory Report


Methodology:
  • Multiple - Based on Individual Components
Clinical Significance

This panel can be helpful in the diagnosis of systemic rheumatic disorders and other autoimmune diseases. Although the test for antinuclear antibodies (ANA) is strongly associated with systemic lupus erythematosus (SLE), the laboratory evaluation for individuals with clinical suspicion of a variety of autoimmune diseases often begins with an ANA screen. This panel simultaneously tests for ANA (using immunofluorescence) as well as the important specific autoantibodies associated with a positive ANA. It also includes testing for complement proteins, rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, polymyositis, anti-phospholipid antibody syndrome, and autoimmune thyroid disease.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 4 days


Coding & Compliance

CDM

00913333


CPT Coding

86038, 86255, 86235 (x9), 86160 (x2), 86147 (x3), 86146 (x3), 83520 (x4), 86200, 86376 If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039). If the DNA (ds) Antibody Screen is positive, then DNA (ds) Antibody Titer will be performed at an additional charge (CPT code(s): 86256).