Jo-1 Autoantibodies

Overview

  • EPIC Code:
  • IMO128
  • Soft Test Code:
  • JOAB1
Alternate Names
  • Anti Jo
  • Anti-Jo-1
  • Histidyl-transferase RNA synthetase
  • JO-1 IgG Autoantibodies
Clinical Significance

A positive result indicates the presence of Jo-1 antibodies and suggests the possibility of polymyositis or other related connective tissue diseases.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum in a SST Gold Top Tube


Transport And Storage

48 hours Refrigerated
30 Days Frozen

Specimen to be transported Refrigerated to PRMC within 48 hours of collection to be frozen by Immunology department to maintain specimen integrity until testing occurs. Do not transport frozen.


Collection Instructions


Minimum Volume

0.5 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

<20 units


Test Comments:

< 20 Units:     Negative
20-39 Units:  Weak Positive
40-80 Units:  Moderate Positive
>80 Units:      Strong Positive


Methodology:
  • Enzyme Immunoassay (EIA)
Clinical Significance

A positive result indicates the presence of Jo-1 antibodies and suggests the possibility of polymyositis or other related connective tissue diseases.


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Friday
Departments
  • Immunology
Turn Around Time

7 days


Coding & Compliance

CDM

00916235


CPT Coding

86235