Chromatin (Nucleosomal) Antibody

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 34088
Alternate Names
  • Chromatin
Clinical Significance

Chromatin Antibody plays a central role in the autoimmune response in systemic lupus erythematosus (SLE). Approximately 90% of patients with SLE have sera that will exhibit reactivity to nucleosomes


Specimen Collection & Preparation

Specimen Requirements:

-OR-

1.0 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume:
0.5 mL Serum*

* This volume does not allow for repeat testing

Rejection Criteria:

Gross hemolysis

Grossly lipemic

Grossly icteric


Transport and Storage:
  • Ambient (18-24°C): 4 Days
  • Refrigerated (2-8°C): 7 Days
  • Frozen (-20° C or colder): 30 Days

Clinical Interpretation

Reference Range:

<1.0 AI Negative


Methodology:
  • Immunoassay (IA)
Clinical Significance

Chromatin Antibody plays a central role in the autoimmune response in systemic lupus erythematosus (SLE). Approximately 90% of patients with SLE have sera that will exhibit reactivity to nucleosomes


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Tuesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00913333


CPT Coding

86235