Alpha Subunit

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 8658
Alternate Names
  • Alpha Subunit of Pituitary
  • Alpha Subunit of the Gonadotropin
  • Glycoprotein Alpha Subunit
  • Gonadotropin Alpha Subunit
  • Pituitary Glycoprotein Hormone Alpha Subunit
Clinical Significance

This assay is useful in the diagnosis and management of various pituitary, placental, pancreatic and hCG-producing tumors. The assay can also be useful for investigations where alpha subunit is increased under various physiological stimuli, e.g., GnRH stimulation and TRH stimulation tests.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

TransportAndStorage

7 days Ambient (transport)
10 days Refrigerated
28 days Frozen

Collection Instructions

Clinical Interpretation

Reference Range:

Males 0.1-0.5 ng/mL
Premenopausal Females 0.1-0.6 ng/mL
Postmenopausal Females 0.1-1.5 ng/mL
Pregnancy (1st and 2nd Trimesters) 35.0-186.0 ng/mL
Hypothyroidism 0.2-3.2 ng/mL


Test Comments:

This test measures the alpha subunit that is common to LH, FSH, TSH and hCG. These hormones are comprised of identical alpha subunits and unique beta subunits that confer biological specificity.


Methodology:
  • Electrochemiluminescence (ECLIA)

Clinical Significance

This assay is useful in the diagnosis and management of various pituitary, placental, pancreatic and hCG-producing tumors. The assay can also be useful for investigations where alpha subunit is increased under various physiological stimuli, e.g., GnRH stimulation and TRH stimulation tests.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Tuesday
Friday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

4 to 11 days


Coding & Compliance

CDM

00913333


CPT Coding

82397