Amiodarone

Specimen Requirements

3.0 mL Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

3.0 mL Serum from a Navy Blue Top Tube - No Additive in a Plastic Vial
or
3.0 mL Plasma from a PST Mint Green Top Tube - Li Heparin in a Plastic Vial
or 
3.0 mL Plasma from a Green Top Tube - Na Heparin in a Plastic Vial
or 
3.0 mL Plasma from 2 Lavender Top Tubes - EDTA in a Plastic Vial
or 
3.0 mL Plasma from a Tan Top Tube Na Heparin/lead free in a Plastic Vial

TransportAndStorage

4 days Refrigerated (Preferred)
1 month Frozen

Collection Instructions

Centrifuge and immediately separate cells

Minimum Volume

1.0 mL

Neonatal Volumne

Reference Range:

Amiodarone: 1.5 - 2.5 mcg/mL
Desmethylamiodarone: 1.5 - 2.5 mcg/mL

Low Detection Limits
Amiodarone: 0.3 mcg/mL
Desmethylamiodarone: 0.3 mcg/mL

Critical Ranges:

Desmethylamiodarone: >2.5 mcg/mL
Toxic Levels have been found as low as 2.0 mcg/mL

Methodology:

• High Performance Liquid Chromatography (HPLC)

CDM

01428194

CPT Coding

82491