Anti-IgA Antibodies, IgG Class

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 2107
Alternate Names
  • Anti-IgA
  • Anti-IgA Ab, IgG, S
  • Anti-IgA Antibody
  • Anti-Immunoglobulin A
  • IgA (Immunoglobulin A) Antibodies
  • IgA Antibodies - IgG, Anti-IgA Antibodies
  • IgG, Anti-IgA Antibodies
  • Immunoglobulin A (IgA) Antibodies
Clinical Significance

For the evaluation of patient with recurrent infection for the possibility of IgA deficiency (IgAD). Patient with IgA deficiency may develop antibodies against IgA that make them suseptible to blood products including intravenous immunoglobulin.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

1.0 mL Serum in a SST Gold Top Tube

TransportAndStorage

1 week ambient
1 week Refrigerated
2 weeks Frozen

Collection Instructions

Testing is due to a transfusion reaction, the specimen should be drawn approximately a minimum of 10 days after the reaction. Testing performed on serum drawn immediately after a reaction may be falsely negative as transfused IgA may deplete anti-IgA antibodies. 

Clinical Interpretation

Reference Range:

Normal, healthy individuals who do not have anti-IgA antibodies contain <99 U/mL. 
The reportable range is 16-1000 U/mL


Methodology:
  • Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA) using human polyclonal IgA coupled to the solid phase

Clinical Significance

For the evaluation of patient with recurrent infection for the possibility of IgA deficiency (IgAD). Patient with IgA deficiency may develop antibodies against IgA that make them suseptible to blood products including intravenous immunoglobulin.


Production Schedule

Sites Performed
  • Eurofins (Previously Viracor)
Days Performed
Thursday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

5 to 7 days


Coding & Compliance

CDM

00913333


CPT Coding

83520