B-Cell Gene Rearrangement

Overview

  • EPIC Code:
  • N/A
  • Soft Test Code:
  • PS
  • Send Out Test Code:
  • Soft Path - BCEL1 & BCEL2
Alternate Names
  • B-Cell Translocations
  • BCell Gene Rearrangement
Included Tests

 B-Cell 1 Gene Rearrangement; B-Cell 2 Gene Rearrangement


Clinical Significance

Detects monoclonal B-cell immunoglobulin gene rearrangement. Interpret in clinical context for diagnosis of leukemia, lymphoma, and plasma cell dyscrasia.

 


Specimen Collection & Preparation

Specimen Requirements

FFPE tissue: Paraffin block

Alternate Specimen

TransportAndStorage

 Refrigerate, and use cold pack for transport, cold pack should not be in direct contact with specimen.

Collection Instructions

Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • Molecular

Clinical Significance

Detects monoclonal B-cell immunoglobulin gene rearrangement. Interpret in clinical context for diagnosis of leukemia, lymphoma, and plasma cell dyscrasia.

 


Production Schedule

Sites Performed
  • NeoGenomics
Departments
  • Sendouts - Pathology
Turn Around Time

7 to 8 days


Coding & Compliance

CPT Coding

81261, 81264