Adenovirus Antigen

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 8355
Alternate Names
  • Adenovirus Ag, Swab
  • Adenovirus Antigen Detection
  • Adenovirus Antigen Detection, Respiratory, DFA
  • Adenovirus Antigen, DFA
  • Adenovirus Direct Antigen Detection
  • Adenovirus Direct Exam
Clinical Significance

Adenovirus causes respiratory tract infections, conjunctivitis, and diarrhea. Infections are most common in individuals who are immunocompromised and in young children. Adenovirus antigen detection is useful to confirm the diagnosis of adenovirus infection in patients with respiratory illness.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

3.0 mL Nasopharyngeal Aspirate in VCM Transport Media
Minimum Volume:
1.0 mL Nasopharyngeal Aspirate*

* This volume does not allow for repeat testing

Collection Instructions:

To maintain optimum viability, place fluid into VCM (equal volumes of fluid and VCM)


Rejection Criteria:

Non-respiratory specimens 

Received in formalin or other fixatives

Received in non-viral transport media such as nucleic acid or bacterial transport media

Sputum

Unpreserved Samples 


Transport and Storage:
  • Refrigerated (2-8°C): 4 Days

    Best recovery is obtained when the specimens are refrigerated following collection and while in transit

  • Iced: 4 Days

     On wet ice following collection and while in transit 

  • Frozen (-20° C or colder): Unacceptable
  • Ultra Frozen (-70° C or colder or by dry ice): 30 Days

    If there will be a long delay before processing, specimens into media it should be frozen at -70ºC or colder and transported on dry ice. 

-OR-

3.0 mL Nasopharyngeal Wash in VCM Transport Media
Minimum Volume:
1.0 mL Nasopharyngeal Wash*

* This volume does not allow for repeat testing

Collection Instructions:

To maintain optimum viability, place fluid into VCM (equal volumes of fluid and VCM)


Rejection Criteria:

Non-respiratory specimens 

Received in formalin or other fixatives

Received in non-viral transport media such as nucleic acid or bacterial transport media

Sputum

Unpreserved Samples 


Transport and Storage:
  • Refrigerated (2-8°C): 4 Days

    Best recovery is obtained when the specimens are refrigerated following collection and while in transit

  • Iced: 4 Days

     On wet ice following collection and while in transit 

  • Frozen (-20° C or colder): Unacceptable
  • Ultra Frozen (-70° C or colder or by dry ice): 30 Days

    If there will be a long delay before processing, specimens into media it should be frozen at -70ºC or colder and transported on dry ice. 

-OR-

3.0 mL Bronchial Lavage Wash in VCM Transport Media
Minimum Volume:
1.0 mL Bronchial Lavage Wash*

* This volume does not allow for repeat testing

Collection Instructions:

To maintain optimum viability, place fluid into VCM (equal volumes of fluid and VCM)


Rejection Criteria:

Non-respiratory specimens 

Received in formalin or other fixatives

Received in non-viral transport media such as nucleic acid or bacterial transport media

Sputum

Unpreserved Samples 


Transport and Storage:
  • Refrigerated (2-8°C): 4 Days

    Best recovery is obtained when the specimens are refrigerated following collection and while in transit

  • Iced: 4 Days

     On wet ice following collection and while in transit 

  • Frozen (-20° C or colder): Unacceptable
  • Ultra Frozen (-70° C or colder or by dry ice): 30 Days

    If there will be a long delay before processing, specimens into media it should be frozen at -70ºC or colder and transported on dry ice. 

-OR-

Nasopharyngeal Swab in VCM Transport Media
Rejection Criteria:

Dry Swabs

Nasal Swabs

Throat Swabs

Non-respiratory specimens 

Received in formalin or other fixatives

Received in non-viral transport media such as nucleic acid or bacterial transport media

Sputum

Unpreserved Samples 


Transport and Storage:
  • Refrigerated (2-8°C): 4 days

    Best recovery is obtained when the specimens are refrigerated following collection and while in transit

  • Iced: 4 Days

     On wet ice following collection and while in transit 

  • Frozen (-20° C or colder): Unacceptable
  • Ultra Frozen (-70° C or colder or by dry ice): 30 Days

    If there will be a long delay before processing, specimens into media it should be frozen at -70ºC or colder and transported on dry ice. 

Clinical Interpretation

Reference Range:

See Laboratory Report


Methodology:
  • Direct Immunofluorescence Assay (DFA)

Clinical Significance

Adenovirus causes respiratory tract infections, conjunctivitis, and diarrhea. Infections are most common in individuals who are immunocompromised and in young children. Adenovirus antigen detection is useful to confirm the diagnosis of adenovirus infection in patients with respiratory illness.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

87260