Campylobacter jejuni Antibody

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 10718
Alternate Names
  • Campylobacter jejuni Antibody, ELISA
Clinical Significance

Campylobacter jejuni is a major cause of sporadic bacterial diarrhea in the United States, with poultry the most important source of infection. Markedly elevated levels of antibodies recognizing C. jejuni typically indicate recent or ongoing infection, even though stool cultures may be negative. Neurological complications may follow C. jejuni infection; approximately 30% of Guillain-Barre' cases are typically associated with recent C. jejuni infection. The basis of this association is apparently molecular mimicry between C. jejuni antigens and gangliosides of neuronal cells.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum from a Red Top Tube in a Plastic Vial


Alternate Specimen

 


TransportAndStorage

7 days Ambient
14 days Refrigerated
30 days Frozen


Collection Instructions

 


Minimum Volume

0.5 mL Serum


Neonatal Volumne

Clinical Interpretation

Reference Range:

 < 0.90


Methodology:
  • Enzyme Linked Immunosorbent Immunoassay (ELISA)

Clinical Significance

Campylobacter jejuni is a major cause of sporadic bacterial diarrhea in the United States, with poultry the most important source of infection. Markedly elevated levels of antibodies recognizing C. jejuni typically indicate recent or ongoing infection, even though stool cultures may be negative. Neurological complications may follow C. jejuni infection; approximately 30% of Guillain-Barre' cases are typically associated with recent C. jejuni infection. The basis of this association is apparently molecular mimicry between C. jejuni antigens and gangliosides of neuronal cells.


Production Schedule

Days Performed
Thursday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

86625