Coxsackie A Antibodies

Included Tests

Coxsackie Antibodies A2, A4, A7, A9, A10, A16

Clinical Significance

Panel currently includes testing against 2, 4, 7, 9, 10, and 16 antigens. Although there is cross-reactivity among the enteroviruses by CF, most healthy people do not have titers >1: 8. Therefore, detectable titers, especially those >1: 32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera

Specimen Requirements

2.0 mL Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

 

TransportAndStorage

7 days Ambient
14 days Refrigerated
30 days Frozen

Collection Instructions

 

Minimum Volume

1.0 mL Serum

Neonatal Volumne

Reference Range:

Coxsackie A2 Ab	<1:8
Coxsackie A4 Ab	<1:8
Coxsackie A7 Ab	<1:8
Coxsackie A9 Ab	<1:8
Coxsackie A10 Ab	<1:8
Coxsackie A16 Ab	<1:8

Methodology:

• Complement Fixation (CF)

Clinical Significance

Panel currently includes testing against 2, 4, 7, 9, 10, and 16 antigens. Although there is cross-reactivity among the enteroviruses by CF, most healthy people do not have titers >1: 8. Therefore, detectable titers, especially those >1: 32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera

Documentation

Limitations: Culture does not usually support growth of coxsackie A viruses

CDM

00913333

CPT Coding

86658 x 6