Copeptin

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 37740
Alternate Names
  • Antidiuretic hormone
  • C-Terminal pro-vasopressin
  • CT-proAVP
Clinical Significance

The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is a reliable surrogate marker for arginine vasopressin (AVP)


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Frozen Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

1.0 mL (0.5 mL) Frozen Serum from a SST Gold Top Tube in a Plastic Vial
or
1.0 mL (0.5 mL) Frozen Plasma from a Green Top Tube - Na Heparin in Plastic Vial 
or
1.0 mL (0.5 mL) Frozen Plasma from a Lavender Top Tube - EDTA in a Plastic Vial

TransportAndStorage

24 hours Ambient 
72 hours Refrigerated
28 days Frozen (transport)

Collection Instructions

 

Clinical Interpretation

Reference Range:

0 to 2 Years: Not Established
3 to < 17 Years: 2.4 - 26.0 pmol/L
> or = 18 Years: < or = 13.7 pmol/L  


Methodology:
  • Immunofluorescence Assay (IFA)

Clinical Significance

The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is a reliable surrogate marker for arginine vasopressin (AVP)


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Monday
Wednesday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

4 to 5 days


Coding & Compliance

CDM

00913333


CPT Coding

86255