BRAF Mutation Analysis

Overview

  • EPIC Code:
  • N/A
  • Soft Test Code:
  • PS
  • Send Out Test Code:
  • Soft Path - BRAF
Alternate Names
  • BRAF V600
Clinical Significance

Useful in selection of melanoma patients for vemurafenib therapy, for determination of prognosis in thyroid and colon cancers, for predicting response to anti-EGFR therapy in colon cancer, and as aid to diagnosis of hairy cell leukemia.


Specimen Collection & Preparation

Specimen Requirements

FFPE tissue: Paraffin block


Alternate Specimen

 


TransportAndStorage

 Refrigerate, and use cold pack for transport, cold pack should not be in direct contact with specimen.


Collection Instructions

Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.


Minimum Volume


Neonatal Volumne

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • Molecular

Clinical Significance

Useful in selection of melanoma patients for vemurafenib therapy, for determination of prognosis in thyroid and colon cancers, for predicting response to anti-EGFR therapy in colon cancer, and as aid to diagnosis of hairy cell leukemia.


Production Schedule

Sites Performed
  • NeoGenomics
Departments
  • Sendouts - Pathology
Turn Around Time

7 to 8 days


Coding & Compliance

CDM

00918076


CPT Coding

81210