BCL2 Translocation, t(14;18)

Overview

  • EPIC Code:
  • N/A
  • Soft Test Code:
  • PS
  • Send Out Test Code:
  • Soft Path - BCL2
Alternate Names
  • B-Cell Leukemia Fusion
  • B-Cell Leukemia Translocation
  • BCL-2 Transolocation (14:8)
Clinical Significance

Useful to confirm diagnosis of follicular lymphoma, monitor therapy effectiveness, and detect minimal residual disease or recurrence


Specimen Collection & Preparation

Specimen Requirements

FFPE tissue: Paraffin block is preferred

Alternate Specimen

TransportAndStorage

 Refrigerate, and use cold pack for transport, cold pack should not be in direct contact with specimen.

Collection Instructions

Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • Molecular

Clinical Significance

Useful to confirm diagnosis of follicular lymphoma, monitor therapy effectiveness, and detect minimal residual disease or recurrence


Production Schedule

Sites Performed
  • NeoGenomics
Departments
  • Sendouts - Pathology
Turn Around Time

7 to 8 days


Coding & Compliance

CDM

00918075


CPT Coding

81402