Alphahydroxyalprazolam; Alphahydroxymidazolam; Alphahydroxytriazolam; Aminoclonazepam; Hydroxyethylflurazepam; Lorazepam; Nordiazepam; Oxazepam; Temazepam
The benzodiazepine class of drugs are traditionally classified as depressants. They are used therapeutically to produce sedation, induce sleep, relieve anxiety, treat muscle spasms, and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of the benzodiazepines is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.
* This volume does not allow for repeat testing
Preserved samples
Transport
| Alphahydroxyalprazolam | <25 ng/mL | |
| Alphahydroxymidazolam | <50 ng/mL | |
| Alphahydroxytriazolam | <50 ng/mL | |
| Aminoclonazepam | <25 ng/mL | |
| Hydroxyethylflurazepam | <50 ng/mL | |
| Lorazepam | <50 ng/mL | |
| Nordiazepam | <50 ng/mL | |
| Oxazepam | <50 ng/mL | |
| Temazepam | <50 ng/mL | |
The benzodiazepine class of drugs are traditionally classified as depressants. They are used therapeutically to produce sedation, induce sleep, relieve anxiety, treat muscle spasms, and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of the benzodiazepines is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.
3 to 4 days
00913333
80346 (HCPCS: G0480)