Alpha-1-Antitrypsin Quantitation

Overview

  • EPIC Code:
  • Soft Test Code:
  • AAT1
  • Send Out Test Code:
  • 235
Clinical Significance

 Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

 

TransportAndStorage

7 days Ambient
7 days Refrigerated
90 days Frozen

Collection Instructions

 

Clinical Interpretation

Reference Range:

83-199 mg/dL


Methodology:
  • Immunoturbidimetric

Clinical Significance

 Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.


Production Schedule

Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 3 days


Coding & Compliance

CPT Coding

82103