25-Hydroxyvitamin D (D2, D3)

Included Tests

Vitamin D, 25-OH, Total; Vitamin D, 25-OH, D₃; Vitamin D, 25-OH, D₂

Clinical Significance

Measurement of serum 25-OH vitamin D concentrations provide a good index of circulating vitamin D activity in patients not suffering from renal disease. Lower than normal 25-OH vitamin D levels can result from a dietary deficiency, poor absorption of the vitamin or impaired metabolism of the sterol in the liver. A 25-OH vitamin D deficiency can lead to bone diseases such as rickets and osteomalacia. Above normal levels can lead to hypercalcemia. This assay employs liquid chromatography tandem mass spectrometry to independently measure and report the two common forms of 25-hydroxy vitamin D: 25-OH D₃ - the endogenous form of the vitamin and 25-OH D₂ - the analog form used to treat 25-OH Vitamin D₃ deficiency.

Patient Preparation

Fasting preferred, but not required

Reference Range:

Methodology:

• Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)

Clinical Significance

Measurement of serum 25-OH vitamin D concentrations provide a good index of circulating vitamin D activity in patients not suffering from renal disease. Lower than normal 25-OH vitamin D levels can result from a dietary deficiency, poor absorption of the vitamin or impaired metabolism of the sterol in the liver. A 25-OH vitamin D deficiency can lead to bone diseases such as rickets and osteomalacia. Above normal levels can lead to hypercalcemia. This assay employs liquid chromatography tandem mass spectrometry to independently measure and report the two common forms of 25-hydroxy vitamin D: 25-OH D₃ - the endogenous form of the vitamin and 25-OH D₂ - the analog form used to treat 25-OH Vitamin D₃ deficiency.

CDM

00913333

CPT Coding

82306