Beta Hydroxybutyrate

Overview

  • EPIC Code:
  • LAB2670
  • Soft Test Code:
  • BHB
Alternate Names
  • Acetone
  • Beta- Hydroxybutyrate
  • Beta- Hydroxybutyrate (BHB)
  • BHB
  • Ketone
Clinical Significance

Beta-hydroxybutyrate(ordered as BHB) is one of three sources of ketone bodies. Its relative proportion in the blood (78%) is greater than the other two keytone bodies which are acetoacetate (20%) and acetone (2%). During periods of ketosis, beta-hydroxybutyrate increases more than acetoacetate with the ratio of beta-hydroxybutyrate/acetoacetate typically between 3:1 and 7:1 in severe ketotic states. beta-hydroxybutyrate has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.


Specimen Collection & Preparation

Specimen Requirements

0.5 mL Serum in a SST Gold Top Tube


Alternate Specimen

0.5 mL Plasma in a PST Mint Green Top Tube - Li Heparin in Plastic Vial
or
0.5 mL Serum from a Red Top Tube in a Plastic Vial
or 
1.0 mL Plasma from a Green Top Tube - Li Heparin in a Plastic Vial


TransportAndStorage

 7 days Refrigerated


Collection Instructions

 


Minimum Volume

0.3 mL Serum


Neonatal Volumne

Clinical Interpretation

Reference Range:

0.0 - 0.28 mmol/L


Methodology:
  • Enzymatic

Clinical Significance

Beta-hydroxybutyrate(ordered as BHB) is one of three sources of ketone bodies. Its relative proportion in the blood (78%) is greater than the other two keytone bodies which are acetoacetate (20%) and acetone (2%). During periods of ketosis, beta-hydroxybutyrate increases more than acetoacetate with the ratio of beta-hydroxybutyrate/acetoacetate typically between 3:1 and 7:1 in severe ketotic states. beta-hydroxybutyrate has been shown to be a better index of ketoacidosis including the detection of subclinical ketosis.


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Chemistry
Turn Around Time

Stat eligble for pediatics only


Stat Eligible

Coding & Compliance

CDM

01424333


CPT Coding

82010