Cytomegalovirus DNA, Qualitative

Overview

  • EPIC Code:
  • LAB2948
  • Soft Test Code:
  • CMVQL
  • Send Out Test Code:
  • 10601
Alternate Names
  • CMV DNA, Qualitative
  • CMV Qual PCR-Newborn
  • Cytomegalovirus DNA, Qualitative Real-Time PCR
Clinical Significance

CMV infections are common and usually asymptomatic. In patients who are immunocompromised, CMV may cause
disseminated, severe disease. CMV may cause birth defects in a minority of infected newborns. DNA methods provide the highest sensitivity and specificity of any method.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Whole Blood Lavender Top Tube - EDTA

Alternate Specimen

1.0 mL Whole Blood in a Yellow Top Tubes - ACD
or 
2.0 mL Plasma from a Lavender Top Tube - EDTA in a Plastic Vial 
or
2.0 mL Plasma from a Yellow Top Tube - ACD in a Plastic Vial 
or
1.0 (0.3) mL CSF from a (Yellow Top Tubes - ACD or Lavender Top Tube - EDTA) in a Plastic Vial 
or 
1.0 (0.3) mL Amniotic Fluid from a (Yellow Top Tubes - ACD or Lavender Top Tube - EDTA) in a Plastic Vial
or
5.0 mL
Urine Collection in a Sterile Plastic Container

Plasma: Collect blood in sterile tubes containing EDTA or ACD as anticoagulant or in Plasma Preparation Tubes (PPT). Store collected whole blood at room temperature and separate plasma from cells within 2 hours of collection. Transfer plasma to sterile, plastic, screw-capped tubes and store refrigerated or frozen. If blood is collected in a PPT tube, centrifuge within 2 hours of collection and store refrigerated or frozen. It is not necessary to transfer the plasma from a PPT tube to aliquot tubes.

Serum, CSF, amniotic fluid, urine, eye fluid, bronchoaveolar brush/wash/lavage and tissue: Collect in a sterile container and store refrigerated or frozen.

Plasma, CSF, tissue, random urine, amniotic fluid, eye fluid, BAL, bronchoaveolar brush/wash, and serum
 Room temperature: 48 hours
 Refrigerated: 8 days
 Frozen: 30 days

TransportAndStorage

48 hours Ambient
8 days Refrigerated

Collection Instructions

 

Clinical Interpretation

Reference Range:

Not Detected


Methodology:
  • Real-Time Polymerase Chain Reaction

Clinical Significance

CMV infections are common and usually asymptomatic. In patients who are immunocompromised, CMV may cause
disseminated, severe disease. CMV may cause birth defects in a minority of infected newborns. DNA methods provide the highest sensitivity and specificity of any method.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 6 days


Coding & Compliance

CDM

00911345


CPT Coding

87496