Clonazepam

Overview

  • EPIC Code:
  • LAB466
  • Soft Test Code:
  • CLONA
  • Send Out Test Code:
  • 340
Alternate Names
  • Klonopin
Clinical Significance

Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum from a Red Top Tube 


Alternate Specimen

2.0 mL Plasma from a Lavender Top Tube - EDTA 
or
2.0 mL Serum from a Navy Blue Top Tube - No Additive
or
2.0 mL Plasma from a Navy Blue Top Tube - EDTA  
or
2.0 mL Plasma from a Green Top Tube - Li Heparin  
or
2.0 mL Plasma from a Green Top Tube - Na Heparin


TransportAndStorage

1 day Ambient
3 days Refrigerated
2 weeks Frozen (Preferred)


Collection Instructions

Collect at trough concentration, immediately before the administration of the next dose

Centrifuge and separate immediately


Minimum Volume

1.0 mL Serum


Neonatal Volumne

Clinical Interpretation

Reference Range:

Clonazapam: 30 - 60 ng/mL


Methodology:
  • Chromatography / Mass Spectrometry

Clinical Significance

Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Tuesday
Thursday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

01426465


CPT Coding

80346