Clonazepam

Overview

  • EPIC Code:
  • LAB466
  • Soft Test Code:
  • CLONA
  • Send Out Test Code:
  • 340
Alternate Names
  • Klonopin
Clinical Significance

Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum from a Red Top Tube 

Alternate Specimen

2.0 mL Plasma from a Lavender Top Tube - EDTA 
or
2.0 mL Serum from a Navy Blue Top Tube - No Additive
or
2.0 mL Plasma from a Navy Blue Top Tube - EDTA  
or
2.0 mL Plasma from a Green Top Tube - Li Heparin  
or
2.0 mL Plasma from a Green Top Tube - Na Heparin

TransportAndStorage

1 day Ambient
3 days Refrigerated
2 weeks Frozen (Preferred)

Collection Instructions

Collect at trough concentration, immediately before the administration of the next dose

Centrifuge and separate immediately

Clinical Interpretation

Reference Range:

Clonazapam: 30 - 60 ng/mL


Methodology:
  • Chromatography / Mass Spectrometry

Clinical Significance

Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Tuesday
Thursday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

01426465


CPT Coding

80346