Barbiturates, GC/MS, Urine

Included Tests

Amobarbital; Butabarbital; Butalbital; Pentobarbital; Phenobarbital; Secobarbital

Clinical Significance

Barbiturates are used as hypnotics, sedatives and anesthetics and are readily absorbed from stomach. Duration of action of barbiturates, in therapeutic doses varies from: 8-16 hours (long acting, e.g., phenobarbital); 4-8 hours (intermediate acting, e.g., amobarbital); 3-6 hours (short acting, e.g., pentobarbital). Barbiturates may enhance other CNS depressants, such as ethanol, morphine derivatives, tranquilizers, and reserpine. Urine should only be used if blood cannot be obtained.

Specimen Requirements

10.0 mL Urine Non Sterile Yellow Capped Plastic Containers (No preservatives)

Alternate Specimen

20.0 mL Urine Sterile Gray Capped Plastic Containers (No preservatives)

TransportAndStorage

7 days Ambient
7 days Refrigerated

Collection Instructions

 

Minimum Volume

5.0 mL Urine

Neonatal Volumne

Reference Range:

Refer to Interpretive Results

Methodology:

• Chromatography / Mass Spectrometry

Clinical Significance

Barbiturates are used as hypnotics, sedatives and anesthetics and are readily absorbed from stomach. Duration of action of barbiturates, in therapeutic doses varies from: 8-16 hours (long acting, e.g., phenobarbital); 4-8 hours (intermediate acting, e.g., amobarbital); 3-6 hours (short acting, e.g., pentobarbital). Barbiturates may enhance other CNS depressants, such as ethanol, morphine derivatives, tranquilizers, and reserpine. Urine should only be used if blood cannot be obtained.

CPT Coding

80345 (Medicare G6043)