Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma based functional test for the determination of APC resistance caused by the factor V Leiden mutatio
* This volume does not allow for repeat testing
Centrifuge light blue-top tube for 15 minutes at approximately 1500 x g within 60 minutes of collection.
Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place plasma into a plastic vial.
Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial.
Plasma must be free of platelets (< 10,000/mcL).
Ambienty Specimen
Refrigerated Specimen
Clotted specimen
Serum
Gross hemolysis
Freeze immediately and ship on dry ice.
≥2.1 Ratio
Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma based functional test for the determination of APC resistance caused by the factor V Leiden mutatio
1 to 2 days
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