Acylcarnitines, Quantitative

Overview

  • EPIC Code:
  • LAB429
  • Soft Test Code:
  • ACYL
  • Send Out Test Code:
  • ACRN
Alternate Names
  • Acylcarnitine, Plasma
  • Acylcarnitines, Quantitative, Plasma
Clinical Significance

Diagnosis of fatty acid beta-oxidation disorders and several organic acidurias.


Specimen Collection & Preparation

Client Notes:

Order Must Include
 A. Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
 B. Patient's age is required on request form for processing.


Specimen Requirements

2.0 mL Plasma from a Green Top Tube - Na Heparin in a Plastic Vial

Alternate Specimen

 

TransportAndStorage

64 days Refrigerated

Collection Instructions

Collect just prior to a meal or feeding.

Clinical Interpretation

Reference Range:

Acetylcarnitine, C:2

1-7 days                2.14-15.89 nmol/mL
8 days-7 years    2.00-27.57 nmol/mL
> or = 8 years      2.00-17.83 nmol/mL

Propionylcarnitine, C3
1-7 days                <0.55 nmol/mL
8 days-7 years    <1.78 nmol/mL
> or = 8 years      <0.88 nmol/mL 

Iso-/Butyrylcarnitine, C4
1-7 days                <0.46 nmol/mL
8 days-7 years    <1.06 nmol/mL
> or = 8 years      <0.83 nmol/mL

 Isovaleryl-/2-Methylbutyrylcarnitine, C5
1-7 days                <0.38 nmol/mL
8 days-7 years    <0.63 nmol/mL
> or = 8 years      <0.51 nmol/mL

Hexanoylcarnitine, C6
1-7 days                <0.14 nmol/mL
8 days-7 years    <0.23 nmol/mL
> or = 8 years      <0.17 nmol/mL

3-OH-Hexanoylcarnitine, C6-OH
1-7 days                <0.08 nmol/mL
8 days-7 years    <0.19 nmol/mL
> or = 8 years      <0.09 nmol/mL

Octenoylcarnitine, C8:1
1-7 days                <0.48 nmol/mL
8 days-7 years    <0.91 nmol/mL
> or = 8 years      <0.88 nmol/mL

Octanoylcarnitine, C8
1-7 days                <0.19 nmol/mL
8 days-7 years    <0.45 nmol/mL
> or = 8 years      <0.78 nmol/mL

Decenoylcarnitine, C10:1
1-7 days                <0.25 nmol/mL
8 days-7 years    <0.46 nmol/mL
> or = 8 years      <0.47 nmol/mL

Decanoylcarnitine, C10
1-7 days                <0.27 nmol/mL
8 days-7 years    <0.91 nmol/mL
> or = 8 years      <0.88 nmol/mL

Glutarylcarnitine, C5-DC
1-7 days                <0.06 nmol/mL
8 days-7 years    <0.10 nmol/mL
> or = 8 years      0.11 nmol/mL 

Dodecenoylcarnitine, C12:1
1-7 days                <0.19 nmol/mL
8 days-7 years    <0.37 nmol/mL
> or = 8 years      <0.35 nmol/mL 

Dodecanoylcarnitine, C12
1-7 days                <0.18 nmol/mL
8 days-7 years    <0.35 nmol/mL
> or = 8 years      <0.26 nmol/mL 

3-OH-Dodecanoylcarnitine, C12-OH
1-7 days                <0.06 nmol/mL
8 days-7 years    <0.09 nmol/mL
> or = 8 years      <0.08 nmol/mL 

Tetradecadienoylcarnitine, C14:2
1-7 days                <0.09 nmol/mL
8 days-7 years    <0.13 nmol/mL
> or = 8 years      <0.18 nmol/mL 

Tetradecenoylcarnitine, C14:1
1-7 days                <0.16 nmol/mL
8 days-7 years    <0.35 nmol/mL
> or = 8 years      <0.24 nmol/mL 

Tetradecanoylcarnitine, C14
1-7 days                <0.11 nmol/mL
8 days-7 years    <0.15 nmol/mL
> or = 8 years      <0.12 nmol/mL

3-OH-Tetradecenoylcarnitine, C14:1-OH
1-7 days                <0.06 nmol/mL
8 days-7 years    <0.18 nmol/mL
> or = 8 years      <0.13 nmol/mL

3-OH-Tetradecanolycarnitine, C14-OH
1-7 days                <0.04 nmol/mL
8 days-7 years    <0.05 nmol/mL
> or = 8 years      <0.08 nmol/mL

Hexadecenoylcarnitine, C16:1
1-7 days                <0.15 nmol/mL
8 days-7 years    <0.21 nmol/mL
> or = 8 years      <0.10 nmol/mL 

Hexadecanoylcarnitine, C16
1-7 days                <0.36 nmol/mL
8 days-7 years    <0.52 nmol/mL
> or = 8 years      <0.23 nmol/mL

3-OH-Hexadecenoylcarnitine, C16:1-OH

1-7 days                <0.78 nmol/mL
8 days-7 years    <0.36 nmol/mL
> or = 8 years      <0.06 nmol/mL 

3-OH-Hexadecanoylcarnitine, C16-OH
1-7 days                <0.10 nmol/mL
8 days-7 years    <0.07 nmol/mL
> or = 8 years      <0.06 nmol/mL 

Linoleylcarnitine, C18:2
1-7 days                <0.12 nmol/mL
8 days-7 years    <0.31 nmol/mL
> or = 8 years      <0.24 nmol/mL 

Oleylcarnitine, C18:1
1-7 days                <0.25 nmol/mL
8 days-7 years    <0.45 nmol/mL
> or = 8 years      <0.39 nmol/mL 

Stearoylcarnitine, C18
1-7 days                <0.10 nmol/mL
8 days-7 years    <0.12 nmol/mL
> or = 8 years      <0.14 nmol/mL 

3-OH-Linoleylcarnitine, C18:2-OH
1-7 days                <0.04 nmol/mL
8 days-7 years    <0.06 nmol/mL
> or = 8 years      <0.06 nmol/mL 

3-OH-Oleylcarnitine, C18:1-OH
1-7 days                <0.03 nmol/mL
8 days-7 years    <0.04 nmol/mL
> or = 8 years      <0.06 nmol/mL


Methodology:
  • Electrospray Tandem Mass Spectrometry (MS/MS)

Clinical Significance

Diagnosis of fatty acid beta-oxidation disorders and several organic acidurias.


Production Schedule

Sites Performed
  • Mayo Laboratory
Days Performed
Monday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

4 to 8 days


Coding & Compliance

CDM

00911168


CPT Coding

82017