Amino Acid Analysis, Quantitative, Urine

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
Alternate Names
  • Amino Acid Analysis, LC/MS, Urine
  • Amino Acid Analysis, Quantitative, Urine
  • Amino Acid Analysis, LC/MS, Urine
Included Tests

 1-Methylhistidine; 3-Methylhistidine;  Alanine; Alpha-Amino Adipic Acid; Alpha-Amino Butyric Acid; Arginine; Asparagine; Aspartic Acid; Beta Alanine; Beta-Amino Isobutyric Acid; Citrulline; Cystathionine; Cystine; Ethanolamine; Gamma-Amino Butyric Acid; Glutamic Acid; Glutamine; Glycine; Histidine; Homocystine; Hydroxylysine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Sarcosine; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Valine; Creatinine Random Urine


Clinical Significance

Amino Acid Analysis, LC/MS, Urine - Amino acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, phenylketonuria, tyrosinemia, citrullinemia, non-ketotic hyperglycinemia, maple syrup urine disease, and homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Random Urine in a Sterile Container

Alternate Specimen

 

TransportAndStorage

7 days Refrigerated
30 days Frozen

Avoid Thaw/Freeze Cycles

Collection Instructions

No Preservatives

Provide patient age (required for correct reference range), sex, a brief clinical history, tentative diagnosis, and the therapy over the last three days (drugs, X-ray, infant formula, diet).

Quest Collection Instruction Sheet

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • Liquid Chromatography / Mass Spectrometry (LC/MS)

Clinical Significance

Amino Acid Analysis, LC/MS, Urine - Amino acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, phenylketonuria, tyrosinemia, citrullinemia, non-ketotic hyperglycinemia, maple syrup urine disease, and homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Monday
Wednesday
Friday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

6 to 9 days


Coding & Compliance

CDM

01425257


CPT Coding

82139, 82570