Amitriptyline

Specimen Requirements

2.0 mL Serum from a Red Top Tube in a Plastic Vial

Alternate Specimen

3.0 mL Plasma from a Lavender Top Tube - EDTA in a Plastic Vial
or
3.0 mL Plasma from a Green Top Tube - Li Heparin in a Plastic Vial 
or
3.0 mL Plasma from a Green Top Tube - Na Heparin in a Plastic Vial

TransportAndStorage

5 days Ambient 
7 days Refrigerated
30 days Frozen

Collection Instructions

Collect as a trough specimen or at least 12 hours after last dose

Minimum Volume

1.5 mL Serum

Neonatal Volumne

Reference Range:

Amitriptyline: No age/sex specific ranges for this test
Nortriptyline: No age/sex specific ranges for this test

Amitriptyline & Nortriptyline: 120 - 250 mcg/L

Low Detection Limit: 5 mcg/L

Critical Ranges:

> 500 mcg/L

Test Comments:

Drug Catagory: Antidepressant

Methodology:

• Chromatography / Mass Spectrometry

CPT Coding

80335