Reference Range:
Collagen/EPI: 69 - 173 Seconds
Collagen/ADP: 54 - 126 Seconds
Coll/EPI Coll/ADP
< =173 sec Not Done
Platelet Function appears adequate. Result consistent with no aspirin ingestion or patient is an Aspirin Non-responder. The effects of ADP receptor blockers such as Clopidogrel are unpredictable.
Coll/EPI Coll/ADP
>173 sec <=126 sec
Results consistent with those of an Aspirin Responder or recent ingestion of antiplatelet medications. Also consistent with any of the following: mild thrombocytopenia, low hematocrit, mild platelet dysfunction, mild von Willebrand disease. The effects of ADP receptor blockers such as Clopidogrel are unpredictable.
Coll/EPI Coll/ADP
>173 sec >126 sec
Results consistent with those of an Aspirin Responder or recent ingestion of antiplatelet medications, such as GPllb/llla receptor inhibitors.Also consistent with any of the following: thrombocytopenia, low hematocrit, platelet dysfunction, von Willebrand disease. The effects of ADP receptor blockers such as Clopidogrel are unpredictable. Additional follow up may be warranted if clinically indicated.
Test Comments:
Collagen/EPI will always be performed. If Collagen/EPI is >173 sec, Collagen/ADP testing will be performed.
Methodology:
- Platelet Function Analyzer
Clinical Significance
Coll/EPI Coll/ADP
< =173 sec Not Done
Platelet Function appears adequate. Result consistent with no aspirin ingestion or patient is an Aspirin Non-Responder.
Coll/ EPI Coll/ADP
>173 sec <=126 sec
Results consistent with those of an Aspirin Responder or recent ingestion of antiplatelet medications. Also consistent with any of the following: mild thrombocytopenia, low hematocrit, mild platelet dysfunction or mild von Willebrand disease.
Coll/EPI Coll/ADP
>173 sec >126 sec
Results consistent with those of an Aspirin Responder or recent ingestion of antiplatelet medications. Also consistent with any of the following or combination of: thrombocytopenia, low hematocrit, platelet dysfunction, von Willebrand disease. Additional follow-up may be warranted if clinically indicated.