Cortisol, Free

Overview

  • EPIC Code:
  • LAB520
  • Soft Test Code:
  • CORF
  • Send Out Test Code:
  • 36423
Alternate Names
  • Cortisol Free
  • Cortisol, Free, LC/MS/MS
  • Free Cortisol
Clinical Significance

Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.


Specimen Collection & Preparation

Patient Preparation

Patient should discontinue taking Biotin, Vitamin B7, or Vitamin H 48 hours before getting blood drawn.


Specimen Requirements:

-OR-

2.0 mL  Serum from a Red Top Tube in a Plastic Vial
Minimum Volume:
0.7 mL Serum*

* This volume does not allow for repeat testing

Rejection Criteria:

Gross hemolysis

Received ambient temperature

Serum separator tube (SST)


Transport and Storage:
  • Ambient (18-24°C): 48 Hours
  • Refrigerated (2-8°C): 7 Days

    Transport 

    Cold Packs

  • Frozen (-20° C or colder): 2 Years

Clinical Interpretation

Reference Range:

Adult  
8:00 - 10:00 A.M. 0.07-0.93 mcg/dL
4:00 - 6:00 P.M. 0.04-0.45 mcg/dL
10:00- 11:00 P.M. 0.04-0.35 mcg/dL


Methodology:
  • Chromatography / Mass Spectrometry
  • Equilibrium Dialysis
Clinical Significance

Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Departments
  • Sendouts - Clinical
Turn Around Time

8 Days


Coding & Compliance

CDM

00911039


CPT Coding

82530