Arbovirus Antibody Panel IgG & IgM, CSF

Overview

  • EPIC Code:
  • LAB3005
  • Soft Test Code:
  • AACSF
  • Send Out Test Code:
  • 18344
Alternate Names
  • Arbovirus Antibody Panel, IFA (CSF)
  • Arbovirus IgG-IgM Abs, CSF
  • Arbovirus Antibody Panel, IFA (CSF)
  • CSF Arboviral Panel
Included Tests

Calif-La Crosse Virus Enceph IgG Antibodies; Calif-La Crosse Virus Enceph IgM Antibodies; Eastern Equine Encephalitis IgG Antibodies; Eastern Equine Encephalitis IgM Antibodies; St. Louis Encephalitis IgG Antibodies; St. Louis Encephalitis IgM Antibodies; Western Equine Encephalitis IgG Antibodies; Western Equine Encephalitis IgM Antibodies


Clinical Significance

Arboviruses are classically defined as viruses that can be transmitted to humans by an arthropod vector. Arboviral diseases of humans may present with four manifestations: fever, encephalitis, hemorrhagic fever and polyarthritis. Fever is the most common sign and is usually benign, mild and undifferentiated, lasting 3-7 days. This panel includes of the following arboviruses that infect the central nervous system: St. Louis encephalitis, California encephalitis and Eastern and Western Equine encephalitis.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL CSF in a Sterile Plastic Vial


Alternate Specimen

 


TransportAndStorage

5 days Ambient
14 days Refrigerated (preferred)
30 days Frozen


Collection Instructions

If multiple Fluid or CSF test are being requested please specify order of importance


Minimum Volume

0.5 mL CSF


Neonatal Volumne

Clinical Interpretation

Reference Range:

IgG < 1:4
IgM < 1:4


Test Comments:

Limitations; False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.


Methodology:
  • Immunofluorescence Assay (IFA)

Clinical Significance

Arboviruses are classically defined as viruses that can be transmitted to humans by an arthropod vector. Arboviral diseases of humans may present with four manifestations: fever, encephalitis, hemorrhagic fever and polyarthritis. Fever is the most common sign and is usually benign, mild and undifferentiated, lasting 3-7 days. This panel includes of the following arboviruses that infect the central nervous system: St. Louis encephalitis, California encephalitis and Eastern and Western Equine encephalitis.


Production Schedule

Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

7 to 8 days


Coding & Compliance

CPT Coding

86651x2, 86652x2, 86653x2, 86654x2