Adenovirus DNA, Quantitative

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 19726
Alternate Names
  • Respiratory Virus
Clinical Significance

This test is used to determine the presence of Adenovirus in a patient's specimen. Organisms may be detected by PCR prior to diagnosis by immunological methods. PCR provides more rapid results than other methods, including culture.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

1.0 mL Whole Blood in a Lavender Top Tube - EDTA
Minimum Volume:
0.6 mL Whole Blood*

* This volume does not allow for repeat testing

Rejection Criteria:

Whole blood or plasma anticoagulated with heparin


Transport and Storage:
  • Ambient: 48 Hour
  • Refrigerated: 7 Days
  • Frozen (-20 C or colder): Unacceptable

-OR-

1.0 mL Urine
Minimum Volume:
0.3 mL Urine*

* This volume does not allow for repeat testing

Transport and Storage:
  • Ambient: 48 Hours
  • Refrigerated: 7 Days
  • Frozen (-20 C or colder): 30 Days

-OR-

1.0 mL CSF in a sterile leak-proof container
Minimum Volume:
0.3 mL CSF*

* This volume does not allow for repeat testing

Transport and Storage:
  • Ambient: 48 Hours
  • Refrigerated: 7 Days
  • Frozen (-20 C or colder): 30 Days

-OR-

1.0 mL Bronchial lavage/wash in a sterile leak-proof container
Minimum Volume:
0.6 mL Bronchial lavage/wash *

* This volume does not allow for repeat testing

Rejection Criteria:

Calcium alginate swabs


Transport and Storage:
  • Ambient: 48 Hours
  • Refrigerated: 7 Days
  • Frozen (-20 C or colder): 30 Days

-OR-

1.0 mL Tracheal lavage/wash in a sterile leak-proof container
Minimum Volume:
0.6 mL Tracheal lavage/wash *

* This volume does not allow for repeat testing

Rejection Criteria:

Calcium alginate swabs


Transport and Storage:
  • Ambient: 48 Hours
  • Refrigerated: 7 Days
  • Frozen (-20 C or colder): 30 Days

-OR-

1.0 mL Nasopharyngeal lavage/wash in a sterile leak-proof container
Minimum Volume:
0.6 mL Nasopharyngeal Lavage/Wash*

* This volume does not allow for repeat testing

Rejection Criteria:

Calcium alginate swabs


Transport and Storage:
  • Ambient: 48 Hours
  • Refrigerated: 7 Days
  • Frozen (-20 C or colder): 30 Days

Clinical Interpretation

Reference Range:

Adenovirus DNA, QN Real-Time PCR: 

   Not Detected copies/mL

Adenovirus DNA, QN Real-Time PCR:

  Not Detected Log copies/mL


Methodology:
  • Real-Time Polymerase Chain Reaction

Clinical Significance

This test is used to determine the presence of Adenovirus in a patient's specimen. Organisms may be detected by PCR prior to diagnosis by immunological methods. PCR provides more rapid results than other methods, including culture.


Documentation

Recommend use in investigation of Acute Hepatitis of Unknown Etiology in Pediatric Patients.

CDC Health Advisory "Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology"

 


Production Schedule

Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00913333


CPT Coding

87799