Amylase Isoenzymes with Reflex to Macroamylase

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 36187
Alternate Names
  • Salivary Amylase
Included Tests

Amylase, Pancreatic Isoenzyme, Salivary Isoenzymes (calculated)


Clinical Significance

Amylase is produced primarily in the pancreas and salivary glands. Isoenzymes may be used to determine the source of an elevated amylase concentration. Macroamylase is a laboratory and not a clinical entity. Amylase can complex with immunoglobulins or other high molecular weight proteins and serum amylase will appear falsely elevated. No clinical symptoms are associated with macroamylasemia.


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum from a Red Top Tube in a Plastic Vial


Alternate Specimen

2.0 mL Serum in a SST Gold Top Tube


TransportAndStorage

Unacceptable Ambient
30 days Refrigerated
30 days Frozen


Collection Instructions


Minimum Volume

1.0 mL Serum


Neonatal Volumne

Clinical Interpretation

Reference Range:

Amylase 21-101 U/L
Pancreatic Isoenzyme 16-46 U/L
Salivary Isoenzymes 4-61 U/L


Test Comments:

If Amylase Isoenzymes are >115 U/L, Macroamylase will be performed at an additional charge (CPT code(s): 82150


Methodology:
  • Polyethylene Glycol Precipitation

Clinical Significance

Amylase is produced primarily in the pancreas and salivary glands. Isoenzymes may be used to determine the source of an elevated amylase concentration. Macroamylase is a laboratory and not a clinical entity. Amylase can complex with immunoglobulins or other high molecular weight proteins and serum amylase will appear falsely elevated. No clinical symptoms are associated with macroamylasemia.


Documentation

Limitations: Oxalate, citrate, and lipemic sera can decrease results


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00913333


CPT Coding

82150