C1 esterase is decreased in angioedema. The inherited form is usually diagnosed in the first two decades of life. The acquired form affects primarily adults with autoimmune or lymphoproliferative disorders. Approximately 15% of patients with hereditary angioedema have a normal concentration of the protein but it is dysfunctional.
1.0 mL Frozen Serum from a Red Top Tube in a Plastic Vial
30 days Frozen
0.2 mL Serum
| ≥68 % | Normal |
| 41-67 % | Equivocal |
| ≤40 % | Abnormal |
limitations: Fifteen percent of patients with the inherited form of the disease will test within range.
C1 esterase is decreased in angioedema. The inherited form is usually diagnosed in the first two decades of life. The acquired form affects primarily adults with autoimmune or lymphoproliferative disorders. Approximately 15% of patients with hereditary angioedema have a normal concentration of the protein but it is dysfunctional.
2 to 3 days
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86161