Anti-Mullerian Hormone, Female

Overview

  • EPIC Code:
  • LAB3094
  • Soft Test Code:
  • AMHFE
  • Send Out Test Code:
  • 37227
Alternate Names
  • AMH
  • AMH-MIS
  • AMH, Female
  • AMH/MIS
  • Anti-Mullerian Hormone
  • Anti-Mullerian Hormone (AMH), Female
  • MIS
  • Mullerian Inhibiting Substance
  • Mullerian Inhibiting Substance,AMH/MIS
Clinical Significance

AMH-MIS may be used in the investigation of ovarian reserve since AMH concentrations in adult women reflect the number of small antral and preantral follicles entering the growth phase of their life cycle. These follicles are proportional to the number of primordial follicles that still remain in the ovary, or the ovarian reserve.
AMH decreases throughout a woman's reproductive life, which reflects the continuous decline of the oocyte/follicle pool with age and, accordingly, ovarian aging.


Specimen Collection & Preparation

Patient Preparation

Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.


Specimen Requirements

0.5 mL  Serum from a Red Top Tube in a Plastic Vial


Alternate Specimen

0.5 mL Plasma from a Green Top Tube, Li Heparin in a Plastic Vial


TransportAndStorage

24 hours Ambient
6 days Refrigerated
28 days Frozen


Collection Instructions


Minimum Volume

0.3 mL Serum


Neonatal Volumne

Clinical Interpretation

Reference Range:

0-17 years Not established
18-25 years 1.02 -14.63 ng/mL
26-30 years 0.69-13.39 ng/mL
31-35 years 0.36-10.07 ng/mL
36-40 years 0.18-5.68 ng/mL
41-45 years 0.01-2.99 ng/mL
>45 years Not established


Methodology:
  • Immunoassay (IA)

Clinical Significance

AMH-MIS may be used in the investigation of ovarian reserve since AMH concentrations in adult women reflect the number of small antral and preantral follicles entering the growth phase of their life cycle. These follicles are proportional to the number of primordial follicles that still remain in the ovary, or the ovarian reserve.
AMH decreases throughout a woman's reproductive life, which reflects the continuous decline of the oocyte/follicle pool with age and, accordingly, ovarian aging.


Documentation

Laboratory Developed Testing


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

00919624


CPT Coding

82166