Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Included Tests

Aldosterone, Plasma Renin Activity; Aldosterone/Plasma Renin Activity Ratio

Clinical Significance

The Aldosterone-renin ratio is used to screen for primary aldosteronism

Specimen Requirements

1.8 mL Frozen Plasma from a Lavender Top Tube - EDTA in a Plastic Vial

Alternate Specimen

 

TransportAndStorage

28 days Frozen

Collection Instructions

Centrifuge and transfer plasma to separate plastic vial and freeze

Minimum Volume

0.8 mL Plasma

Neonatal Volumne

Reference Range:

Aldosterone

Adult

Upright 8:00-10:00 A.M.

≤28

ng/dL

Upright 4:00-6:00 P.M.

≤21

ng/dL

Supine 8:00-10:00 A.M.

3-16

ng/dL

Pediatric

1-12 Months

2-70

ng/dL

1-4 Years

2-37

ng/dL

5-9 Years

≤9

ng/dL

10-13 Years

≤21

ng/dL

14-17 Years

≤35

ng/dL

Infants

Premature (31-35 Weeks)

≤144

ng/dL

Term

≤217

ng/dL

Tanner Stages

II-III Males

1-13

ng/dL

II-III Females

2-20

ng/dL

IV-V Males

3-14

ng/dL

IV-V Females

4-32

ng/dL

Plasma Renin Activity	0.25-5.82		ng/mL/h
Aldosterone/PRA Ratio	0.9-28.9		Ratio

Methodology:

• Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)

Clinical Significance

The Aldosterone-renin ratio is used to screen for primary aldosteronism

CDM

00913333

CPT Coding

82088, 84244