Actin Antibody IgG

Overview

  • EPIC Code:
  • IMO206
  • Soft Test Code:
  • SMA1
  • Send Out Test Code:
  • 15043 / 15043X
Alternate Names
  • ACTA
  • Anti-Smooth Muscle Antibody
  • Anti-smooth muscle Antibody Titer
  • ASMA
  • F-Actin Antibody
  • SM Muscle Actin Ab
  • SMA
  • Smooth Muscle (Actin) Antibody
  • Smooth Muscle Antibody

Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum from a Red Top Tube in a Plastic Vial


Alternate Specimen

0.5 mL Serum in a SST Gold Top Tube


TransportAndStorage

14 days Ambient
14 days Refrigerated
30 days Frozen


Collection Instructions

 


Minimum Volume

0.25 mLSerum


Neonatal Volumne

Clinical Interpretation

Reference Range:

<20 U Negative
> 20 U Positive


Test Comments:

Antibodies recognizing actin are the main component of smooth muscle antibodies associated with autoimmune liver disease. Actin antibodies are found in approximately 75% of patients with autoimmune hepatitis (AIH) type 1, approximately 65% of patients with autoimmune cholangitis, approximately 30% of patients with primary biliary cirrhosis, and approximately 2% of healthy people. High values are closely correlated with AIH type 1.

 


Methodology:
  • Enzyme Linked Immunosorbent Immunoassay (ELISA)

Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

3 to 5 days


Coding & Compliance

CDM

00917148


CPT Coding

86015