Apolipoprotein B

Clinical Significance

Apolipoprotein B (APO B) has been reported to be a powerful indicator of CAD. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol

Patient Preparation

Fasting 12 hours

Specimen Requirements

1.0 mL Serum from a SST Gold Top Tube

Alternate Specimen

1.0 mL Serum from a Red Top Tube in a Plastic Vial

TransportAndStorage

7 days Ambient
10 days Refrigerated
30 dayss Frozen

Collection Instructions

Avoid moderately or grossly lipemic, icteric, or hemolyzed specimens

Minimum Volume

0.5 mL Serum

Neonatal Volumne

Reference Range:

<90 mg/dL

Risk Category
Optimal	<90 mg/dL
Moderate	90-119 mg/dL
High	≥120 mg/dL

Cardiovascular event risk category cut points (optimal, moderate, high) are based on National Lipid Association recommendations- Jacobson TA et al. J of Clin Lipid. 2015; 9: 129-169 and Jellinger PS et al. Endocr Pract. 2017;23(Suppl 2):1-87.

Methodology:

• Immunoassay (IA)

Clinical Significance

Apolipoprotein B (APO B) has been reported to be a powerful indicator of CAD. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol

CDM

00910524

CPT Coding

82172