Overview
EPIC Code:
Soft Test Code:
- MSOT
Send Out Test Code:
- 178
Included Tests
ADmark® ApoE Genotype Analysis and Interpretation (Symptomatic)
ADmark® Phospho-Tau/Total-Tau/A Beta 42 CSF Analysis and Interpretation (Symptomatic)
Clinical Significance
Detection of ApoE2, E3, E4 alleles and levels of Phosphorylated-Tau protein, Total-Tau protein and Ab42.
Specimen Collection & Preparation
Client Notes:
Contact Client Response Center at 266-1500 option 1 and request the Polypropylene transfer tubes
Specimen Requirements
2.0 mL CSF in sterile Polypropylene transfer tube
AND
8.0 mL Whole Blood in Lavender Top Tube(s) - EDTA
Alternate Specimen
TransportAndStorage
Refrigerate if necessary for a maximum of 24 hours, Whole blood-room temperature, avoid freezing
Ship;CSF: Must be shipped on a cold pack or frozen. Whole blood: Ship room temperature or refrigerated, avoid freezing.
Collection Instructions
CSF must be collected in a sterile polypropylene tube.
Minimum Volume
1 mL CSF; 6 mL whole blood
Neonatal Volumne
Clinical Interpretation
Reference Range:
Correlation of levels of markers of Phosphorylated-Tau, Total-Tau, and Ab42, Presence of ApoE2, E3, E4 alleles
Methodology:
- Restriction Fragment Length Polymorphism (RFLP)
- Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Clinical Significance
Detection of ApoE2, E3, E4 alleles and levels of Phosphorylated-Tau protein, Total-Tau protein and Ab42.
Documentation
Athena does not perform ApoE testing for individuals under the age of 18. Pre-test and post-test genetic counseling is strongly recommended.
Production Schedule
Sites Performed
- Athena Diagnostics
Departments
- Sendouts - Miscellaneous
Turn Around Time
14 to 21 days
Coding & Compliance
CDM
00913334
CPT Coding
81401 x1, 83520 x 3