Dehydroepiandrosterone Sulfate

Overview

  • EPIC Code:
  • LAB524
  • Soft Test Code:
  • DHEAS
Alternate Names
  • DHEA Sulfate
Clinical Significance

DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum in a SST Gold Top Tube

Alternate Specimen

1.0 mL Serum from a Red Top Tube in a Plastic Vial

TransportAndStorage

4 hours Ambient
6 days Refrigerated (Preferred)
28 days Frozen

Collection Instructions

Early morning specimen preferred

Clinical Interpretation

Reference Range:

Pediatric:
< 1 week 108-607 µg/dL
1-4 weeks 31.6-431 µg/dL
1-12 months 3.4-124 µg/dL
1-4 years 0.47-19.4 µg/dL
5-9 years 2.8-85.2 µg/dL 

Male: 
10-14 24.1 - 247 µg/dL
15-19 70.2-492 µg/dL
20-24 211-492 µg/dL
25-34 160-449 µg/dL
35-44 88.9-427 µg/dL
45-54 44.3-331 µg/dL
55-64 51.7-295 µg/dL
65-74 33.6-249 µg/dL
>=75 16.2-123 µg/dL 

Female: 
10-14 33.9-280 µg/dL
15-19 65.1-368 µg/dL
20-24 148-407 µg/dL
25-34 98.8-340 µg/dL
35-44 60.9-337 µg/dL
45-54 35.4-256 µg/dL
55-64 18.9-205 µg/dL
65-74 9.40-246 µg/dL
>=75 12.0-154 µg/dL


Methodology:
  • Electrochemiluminescence (ECLIA)

Clinical Significance

DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Chemistry

Coding & Compliance

CDM

01429458


CPT Coding

82627