Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
MALE:
Urethral Swab collected in a APTIMA® Unisex Swab Kit (white label)
FEMALE:
Vaginal swab in 0.7 mL APTIMA® Vaginal Swab Collection Kit (orange label)
Collection Instructions:
MALE:
Male Urethral Swabs: Follow instructions in the APTIMA® Unisex Swab Specimen Collection Kit (white label).
Excess mucus should be removed prior to sampling.
FEMALE:
Vaginal Swabs: Follow instructions in the APTIMA® Vaginal Swab Collection Kit or Multitest Collection Kit (orange label).
Minimum Volume:
0.3 mL
Transport & Storage: Temperature/Stability:
14 days Ambient (transport)
14 days Refrigerated
30 days Frozen
Rejection Criteria:
See Documentation area for all rejection criteria
Reference Range:
Mycoplasma hominis, Real-Time PCR
Not detected
Mycoplasma genitalium, Real-Time PCR
Not detected
Ureaplasma species, Real-Time PCR
U. parvum DNA - Not detected
U. urealyticum DNA - Not detected
Critical Ranges:
Test Comments:
Methodology:
Real-Time Polymerase Chain Reaction
Clinical Significance:
Mycoplasma and Ureaplasma spp. have been associated with genital tract infection. M. genitalium has been implicated in cervicitis, endometritis, and PID. M. hominis has also been associated with cervicitis and is present in increased numbers in vaginosis. Ureaplasma spp. have been linked to upper genitourinary tract infection and to premature labor and abortion. Because of their nature, these organisms are not routinely cultured and are better detected by molecular methods.
Recently, by molecular means two groups of Ureaplasma spp. have been distinguished- U. parvum and U. urealyticum, with the former being more prevalent in the lower genital tract of a healthy woman. It is not clear which species more predominantly causes infection. M. hominis and the ureaplasmas appear to be opportunists when they infect the upper genitourinary tract. These organisms have also been targeted as having a possible role in infertility, although this remains a gray area.
Documentation:
Rejection Criteria:
Transport tubes with 2 swabs • Transport tubes with Non-APTIMA® swabs • Swab transport tubes with no swab • Swab submitted in non-APTIMA® transport containers • Urine samples where the fluid level is not between the black fill lines • Urine submitted in non-APTIMA® transport containers • Female urine
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
4 to 5 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Chantilly
PHL Test Code:
MSOT
EPIC Test Code:
MISC
Send Out Test Code:
91477
Alternate Test Names:
SureSwab®, Mycoplasma Urea Plasma ; SureSwab®, Mycoplasma/Ureaplasma Panel; SureSwab®, Mycoplasma/Ureaplasma Panel, PCR
Included Tests:
Mycoplasma genitalium; Mycoplasma hominis; Ureaplasma species
CPT Coding:
87563, 87798 (x3)