Last Modified:
5/25/2023 3:05:07 PM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
2.0 mL Whole Blood in a Lavender Top Tube - EDTA
Collection Instructions:
Minimum Volume:
0.5 mL Whole Blood
Transport & Storage: Temperature/Stability:
5 days Ambient (transport)
30 days Refrigerated
30 days Frozen
Rejection Criteria:
Non-whole blood samples • Non-EDTA (lavender-top) tube
Reference Range:
PEth 16:0/18:1 (POPEth)<20 ng/mL
PEth 16:0/18:2 (PLPEth)<20 ng/mL
Critical Ranges:
Test Comments:
Methodology:
Chromatography/Mass Spectrometry
Clinical Significance:
Alcohol abuse remains a significant public health challenge in the United States. As a long-term, specific and direct biomarker of alcohol consumption, Phosphatidylethanol (PEth) is a group of phospholipids formed in the presence of ethanol and incorporated into the phospholipid membrane of red blood cells. PEth detection is suggestive of ethanol ingestion over multiple days. PEth is detectable for 1-2 weeks. The predominant PEth homologues are PEth 16:0/18:1 (POPEth) and PEth 16:0/18:2 (PLPEth), which account for 37-46% and 26-28% of the total PEth homologues, respectively.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Departments:
PHL Test Code:
MSOT
EPIC Test Code:
MISC
Send Out Test Code:
12198
Alternate Test Names:
Alcohol Metabolite; Alcohol use biomarkers; PEth
Included Tests:
PEth 16:0/18:1 (POPEth); PEth 16:0/18:2 (PLPEth)
CPT Coding:
80321 (HCPCS: G0480)
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