Sjogren Antibodies

Last Modified: 1/3/2023 8:58:42 AM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

2.0 mL Serum in a SST Gold Top Tube
Collection Instructions:  
Minimum Volume: 1.0 mL
Transport & Storage: Temperature/Stability: 8 hrs Ambient
2 days Refrigerated
28 days Frozen

Do not transport Frozen.
Specimen to be transported Refrigerated to PRMC within 48 hours of collection to be frozen by Immunology department to maintain specimen integrity until testing occurs.
Rejection Criteria: Gross hemolysis; grossly lipemic, grossly icteric, microbial contamination may interfere
Reference Range: SS-A Ab 
Negative < 20 units

SS-B Ab 
Negative < 20 units
Critical Ranges:  
Test Comments:  
Methodology: EIA
Clinical Significance: Sjogren's Antibody (SS-B) is detected in approximately 15% of patients with Sjogren's syndrome. Sjogren's Antibody (SS-B) is present only if Sjogren's Antibody (SS-A) is also detected. The presence of both antibodies (SS-A and SS-B) strengthen the diagnosis of Sjogren's syndrome and conveys prognostic information.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Days Performed: Friday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: SJOA1
EPIC Test Code: IMO84
Alternate Test Names: SS-A and SS-B IgG Antibodies
Included Tests: Sjogrens Antibody A (SS-A)(Ro Antibody / Anti Ro); Sjogrens Antibody B (SS-B)(La Antibody / Anti La)
CPT Coding: 86235 x 2

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