Sjogren Antibodies

Overview

  • EPIC Code:
  • IMO84
  • Soft Test Code:
  • SJOA1
Alternate Names
  • SS-A and SS-B IgG Antibodies
Included Tests

Sjogrens Antibody A (SS-A)(Ro Antibody / Anti Ro); Sjogrens Antibody B (SS-B)(La Antibody / Anti La)


Clinical Significance

Sjogren's Antibody (SS-B) is detected in approximately 15% of patients with Sjogren's syndrome. Sjogren's Antibody (SS-B) is present only if Sjogren's Antibody (SS-A) is also detected. The presence of both antibodies (SS-A and SS-B) strengthen the diagnosis of Sjogren's syndrome and conveys prognostic information.


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum in a SST Gold Top Tube


Transport And Storage

8 hrs Ambient
2 days Refrigerated
28 days Frozen

Do not transport Frozen.
Specimen to be transported Refrigerated to PRMC within 48 hours of collection to be frozen by Immunology department to maintain specimen integrity until testing occurs.


Collection Instructions

 


Minimum Volume

1.0 mL


Neonatal Volume

Clinical Interpretation

Reference Range:

SS-A Ab 
Negative < 20 units

SS-B Ab 
Negative < 20 units


Methodology:
  • Enzyme Immunoassay (EIA)
Clinical Significance

Sjogren's Antibody (SS-B) is detected in approximately 15% of patients with Sjogren's syndrome. Sjogren's Antibody (SS-B) is present only if Sjogren's Antibody (SS-A) is also detected. The presence of both antibodies (SS-A and SS-B) strengthen the diagnosis of Sjogren's syndrome and conveys prognostic information.


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Friday
Departments
  • Immunology

Coding & Compliance

CDM

01426236; 01426235


CPT Coding

86235 x 2