Porphyrins, Fractionated

Last Modified: 8/12/2021 8:48:21 AM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

2.0 mL Plasma in a Amber Plastic Vial from a Green Top Tub - Na Heparin 
Collection Instructions:

Collect blood sample wrap with foil

Separate plasma by centrifugation. Avoid hemolysis.

Remove plasma to a light-protected Amber tube. 

Freeze immediately after separation.
Minimum Volume: 0.4 mL Plasma
Transport & Storage: Temperature/Stability: 8 hours Ambient
8 hours Refrigerated
90 days Frozen (Transport)
Rejection Criteria: Hemolysis • Received room temperature • Received refrigerated • Not protected from light • Serum Separator Tube (SST®)
Reference Range:
Uroporphyrin ≤0.2 mcg/L
Heptacarboxyporphyrin ≤0.2 mcg/L
Hexacarboxyporphyrin ≤0.3 mcg/L
Pentacarboxyporphyrin ≤0.4 mcg/L
Coproporphyrin ≤0.8 mcg/L
Protoporphyrin 0.4-4.8 mcg/L
Total Porphyrins 1.0-5.6 mcg/L
Critical Ranges:  
Test Comments:  
Methodology: High Performance Liquid Chromatography (HPLC)
Clinical Significance: Porphyrins, Fractionated, Plasma - Porphyria is a group of distinct disorders characterized by the abnormal accumulation of porphyrins or porphyrin precursors. Porphyrin fractionation of plasma is useful in diagnosing certain types of porphyrias and excluding porphyrias in patients with chronic renal failure suspected of having a porphyria
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 4 to 5 days
Days Performed: Tuesday, Thursday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: MSOT
EPIC Test Code: MISC
Send Out Test Code: 5519
Alternate Test Names: Porphyrins, Fractionated, Plasma
Included Tests: Coproporphyrin; Uroporphyrin; Heptacarboxyporphyrin; Hexacarboxyporphyrin; Pentacarboxyporphyrin;  Protoporphyrin; Total Porphyrins
CPT Coding: 82542

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