Last Modified:
10/4/2018 6:35:36 AM
Specimen Requirements:
2.0 mL Serum from a SST Gold Top Tube in a Plastic Vial
Collection Instructions:
Collect 5 mL whole blood in a serum separator tube (red-top), and separate serum before submitting to testing laboratory
Minimum Volume:
1.0 mL Serum
Transport & Storage: Temperature/Stability:
21 days Refrigerated
Rejection Criteria:
Hemolysis | Lipemia | Icterus | Ambient | Frozen
Reference Range:
| Platelet Ab, Indirect (IgG) |
Negative |
| Platelet Ab, Indirect (IgM) |
Negative |
| Platelet Ab, Indirect (IgA) |
Negative |
Methodology:
Flow Cytometry (FC)
Clinical Significance:
The identification of circulating platelet antibodies is useful in order to identify immune-mediated platelet destruction. Disorders associated with immune platelet destruction include isoimmune neonatal thrombocytopenia, drug induced thrombocytopenia, drug sensitivities, allergies and post transfusion purpura. The destruction is either autoimmune, where a malfunction in the immune response results in the production of antibodies directed against 'self' platelet specific antigens; or else platelet destruction occurs when the patient received platelet-specific antibodies from an outside source such as a non-compatible blood transfusion or maternal transfer across the placental barrier. In either of the above situations, the detection of platelet antibodies is useful in order to determine if an immune basis is responsible for the thrombocytopenia observed clinically
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
3 to 6 days
Days Performed:
Tuesday, Saturday
Sites Performed:
Quest - Chantilly to San Juan Capistrano
PHL Test Code:
MSOT
Send Out Test Code:
34327
Alternate Test Names:
Circulating Platelet Antibody; Platelet Ab Screen; Platelet Antibodies, Indirect (IgG, IgM, IgA) ; Platelet Antibodies, Indirect IgG, IgM, IgA; Serum Platelet Antibody
CPT Coding:
86022 x 3
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