Pentobarbital

Last Modified: 12/28/2022 12:56:33 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:
Specimen Requirements:  
Collection Instructions:   Collect just prior to next dose
Transport & Storage: Temperature/Stability: 5 days Ambient
7 Days Refrigerated
Not Established Frozen
Rejection Criteria: Serum separator tube (SST) • Any other tube with additives
Reference Range:  1.0-5.0 mg/L
Critical Ranges:  
Test Comments:  
Methodology: Chromatography/Mass Spectrometry
Clinical Significance: Used as a hypnotic, sedative and anesthetic. Readily absorbed from stomach. Duration of action, in therapeutic doses, is approximately 3-6 hours (short acting Barb). Barbiturates may enhance other CNS depressants, such as ethanol, opiates, tranquilizers, resperine, etc.

Pentobarbital is given IV to reduce intracranial pressure and lower cerebral oxygen demand in patients with severe head trauma, Reye's syndrome, or anoxic brain damage. Pentobarbital use in this case requires a much higher therapeutic drug concentration
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 3 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: MSOT
EPIC Test Code: MISC
Send Out Test Code: 9852 [700X]
Alternate Test Names: Nembutal
Included Tests:  
CPT Coding: 80345; G0480

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