Medical Necessity Documentation:
Client Notes:
Patient Preparation:
12 hour fasting preferred but not required
Specimen Requirements:
4.0 mL Serum from a SST Gold Top Tube placed in Opaque Transport Bag
Collection Instructions:
Centrifuge and separate from cells within 2 hours of collection
Protect from light by placing in a black opaque transport bag.
Minimum Volume:
2.0 mL Serum
Transport & Storage: Temperature/Stability:
24 hours Refrigerated
Reference Range:
Vitamin B12:
200-900 pg/mL
Reflex
Homocysteine:
(Adult <60 years of age): 4.5-15 umol/L
Methylmalonic Acid:
87-318 nmol/L
Critical Ranges:
Test Comments:
A Homocysteine and Methylmalonic Acid will automatically be performed and charged when the VB12 is 150-400 pg/mL.
B12: Patients taking vitamin supplements containing high doses of biotin (>5 mg/day) may have falsely increased test results generated.
Excessive light exposure may alter Vitamin B12 and Folate values.
Methodology:
Chemiluminescence, Mass Spectrometry
Clinical Significance:
Homocysteine and Methylmalonic Acid, in conjunction with Vitamin B12, may be useful for the identification of early or subclinical Vitamin B12 deficiency.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
2 to 4 days
Days Performed:
Sunday, Monday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Parkview Regional Medical Center, Quest - Chantilly
PHL Test Code:
B12R
EPIC Test Code:
LAB3133
Send Out Test Code:
34879
Alternate Test Names:
Vitamin B12 with Reflexes
Included Tests:
Homocysteine; Methylmalonic Acid; Vitamin B12 (B12)
CPT Coding:
82607 (Reflex 83090 and 83921)