Vitamin K

Last Modified: 2/20/2023 2:10:53 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:

Fasting for a minumum of 8 hours required. 
Patient should refrain from eating liver and taking multivitamins or vitamin K at least 24 hours before sample collection.
Specimen Requirements: 1.0 mL Frozen Plasma from a Lavender Top Tube - EDTA in a Amber Vial
Collection Instructions: Centrifuge within 1 hour of collection, transfer plasma into amber vial, freeze immediately

Protect from Light by placing the plasma in an Amber Vial or other in the dark protocols

If unable to centrifuge immediately, sample should be covered with aluminum foil (or amber specimen bag) immediately and placed on ice until plasma or serum can be separated from cells
Minimum Volume: 0.5 mL Plasma
Transport & Storage: Temperature/Stability: 24 hours Ambient
24 hours Refrigerated 
3 months Frozen (Transport)

Do not thaw

Samples received frozen but not protected from light are acceptable.
Rejection Criteria: Grossly lipemic • Gross hemolysis
Reference Range:

130 - 1500 pg/mL
Critical Ranges:  
Test Comments:  
Methodology: HPLC
Clinical Significance: Vitamin K is a required cofactor for the synthesis of factors 2, 7, 9, and 10, and proteins C and S. Deficiencies of vitamin K lead to bleeding. Warfarin acts as an anticoagulant because it is a vitamin K antagonist.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 3 to 4 days
Days Performed: Tuesday, Wednesday, Thursday
Sites Performed: Quest - Chantilly
PHL Test Code: VITK
EPIC Test Code: LAB1110
Send Out Test Code: 36585
Included Tests:  
CPT Coding: 84597

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