Last Modified:
9/28/2023 7:27:33 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Patients taking calcineurin inhibitors should stop their medication for 72 hours prior to draw
Specimen Requirements:
1.5 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
Minimum Volume:
1.0mL Serum
Transport & Storage: Temperature/Stability:
7 days Ambient (Transport)
7 days Refrigerated
30 days Frozen
Rejection Criteria:
Gross hemolysis • Gross Lipemia • Icteric specimen • Specimen other than serum • Serum Separator Tube (SST/PST)
Reference Range:
<16 %
Critical Ranges:
Test Comments:
Methodology:
Cell Culture (CC) • Immunoassay (IA)
Clinical Significance:
Chronic Urticaria (CU) is a common skin disorder affecting 1 to 6% of the general population. It is characterized by repeated occurrence of short-lived cutaneous wheals accompanied by redness and itching. Autoimmune urticaria is defined by the presence of a functional IgG antibody to high-affinity IgE receptor (Fc epsilon RI alpha) or IgE. These antibodies trigger mast cell and basophil degranulation by the engagement of Fc epsilon receptor. Functional IgG antibody to the receptor has been identified in approximately 30-40% of patients with CU, and anti IgE antibody has been identified in another 5%-10%.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
3 days
Days Performed:
Tuesday, Thursday
Departments:
Sites Performed:
Quest - Chantilly to San Juan Capistrano
PHL Test Code:
MSOT
EPIC Test Code:
MISC
Send Out Test Code:
16838
Alternate Test Names:
Anti-IgE Receptor, CU; Chronic Urticaria (CU); FC Epsilon Receptor Antibody,CU; FC Epsilon Receptor Antibody,CU (Chronic Urticaria; FCER1
Included Tests:
CPT Coding:
86343
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